Moving from Durham, NC to St. Louis, MO
A move from Durham, NC to St. Louis, MO covers 772 mi and around 14h 52m of driving through 7 state(s). At this range plan for a two- or three-day drive, a hauler or PODS container for household goods, and a noticeable shift in weather, tax jurisdiction, and housing market. The sections below pull the current BEA, Census, Zillow, BLS, and NOAA figures into one view.
772 mi Β· 14h 52m by car Β· MO β IL β IN β KY β VA β WV β NC
Distance & route
| Route through | MO β IL β IN β KY β VA β WV β NC |
|---|---|
| Primary highways | I 64, US 460, US 150 |
| Major cities en route | Evansville, Winston Salem, High Point, Greensboro, Cary |
Route via OSRM driving profile. Actual time varies with traffic and season.
Cost of living
| Durham | St. Louis | U.S. avg | |
|---|---|---|---|
| All items (RPP) | 97.572 | 95.088 | 100.0 |
| Rents | 89.317 | 69.921 | 100.0 |
| Goods | 96.621 | 99.996 | 100.0 |
| Services | 98.934 | 79.024 | 100.0 |
Overall cost of living in St. Louis and Durham is within Β±5% on the BEA Regional Price Parity (2024) β plan your budget on category-level differences instead.
Source: BEA Regional Price Parities (MSA-level Β· MSA-level); 2024.
Housing prices
YoY change: Durham -2.5%, St. Louis β. Snapshot: 2026-03. Data provided by Zillow.
Climate
| 1991β2020 normals | Durham | St. Louis |
|---|---|---|
| Annual avg temperature | 58Β°F | 58Β°F |
| January avg low | 28Β°F | 25Β°F |
| July avg high | 87Β°F | 90Β°F |
| Annual snowfall | β | β |
| Annual precipitation | 48.6" | 43.9" |
Annual average temperatures in Durham (58.4Β°F) and St. Louis (58.0Β°F) stay within 5Β°F of each other (NOAA normals).
Source: NOAA U.S. Climate Normals 1991β2020 (stations: DURHAM, NC US, ST LOUIS SCI CTR, MO US).
Demographics
| ACS 5-year 2023 | Durham | St. Louis |
|---|---|---|
| Population | 288,465 | 293,109 |
| Median household income | $79,234 | $55,279 |
| Median age | 34.8 | 36.6 |
| Bachelor's degree or higher | 28.8% | 22% |
| Avg household size | 2.34 | 2.03 |
Median household income in St. Louis is 2.5% below Durham ($79,234 vs $55,279, ACS 5-year 2023).
Source: U.S. Census Bureau, ACS 5-year 2023.
Jobs & wages
Top occupations in St. Louis MSA
| Occupation | Employment | Median wage |
|---|---|---|
| Office and Administrative Support Occupations | 162,150 | $43,310 |
| Food Preparation and Serving Related Occupations | 119,600 | $29,980 |
| Transportation and Material Moving Occupations | 115,380 | $39,330 |
| Sales and Related Occupations | 108,510 | $35,500 |
| Management Occupations | 94,750 | $100,940 |
Source: BLS Occupational Employment and Wage Statistics.
Moving between North Carolina and Missouri
State income-tax top marginal rates are from the Tax Foundation, updated annually. Check Missouri's DMV for the current deadline to transfer driver license and vehicle registration after establishing residency. Consult a tax professional for your specific filing situation β state tax treatment depends on residency, sourcing, and reciprocity agreements.
Best time to move
Moving companies typically charge 20β30% more between Memorial Day and Labor Day (peak season). October through April offers the lowest rates and better mover availability.
To avoid mid-semester school transfers, most U.S. families schedule moves between mid-June and mid-August. Public school calendars typically run late August or early September through late May or early June.
Winter driving along this route
- I-75 at Jellico Mountain (KY/TN border) sees chain requirements in winter storms.
- I-64 across Afton Mountain and I-77 at Fancy Gap see chain requirements in winter storms.
- I-77 at Flat Top Mountain and I-64 through the Greenbrier Valley see chain requirements in winter storms.
- I-40 through Pigeon Gap and I-26 over Saluda Grade can see chain requirements in winter storms.
State DOT 511 phone or web services provide real-time road conditions year-round.
Packing & arrival checklist
- Tornadoes are common April through June β identify a safe room or interior space on day one.
- Arrange utility connection (power, internet, gas, water) two weeks ahead of move-in.
- Update mailing address with USPS change-of-address within the first week post-move.
- Register to vote in Missouri after establishing residency.
Frequently asked
How does household income compare in Durham vs St. Louis?
Median household income on the Census ACS 5-year (2023) is $55,279 in St. Louis vs $79,234 in Durham β a 30.2% lower figure. Compare this against the cost-of-living gap above when budgeting.
When is the best time to move from Durham to St. Louis?
Moving companies usually charge 20β30% less between October and April (off-peak). Memorial Day through Labor Day is peak pricing. For a 772 mi drive, weather on the route matters too β see the timing section above for state-specific winter warnings.
Is St. Louis more expensive than Durham?
Based on BEA Regional Price Parities (2024), overall price level in St. Louis is 2.5% lower than Durham (95.088 vs 97.572, U.S. average = 100). Rent and services typically carry most of this gap.
How does the job market in St. Louis compare to Durham?
BLS Occupational Employment and Wage Statistics show median wages of $47,490 in the St. Louis MSA vs $58,480 in the Durham MSA, on total employment of 1,325,480 and 336,100 respectively. Top occupations on the destination side appear in the Jobs & wages section above.
How far is St. Louis, MO from Durham, NC?
The driving distance is 772 mi and the route typically takes 14h 52m via I 64 and US 460. The trip crosses 7 state(s). Actual time varies with traffic and season.
Plan the move
Estimate costs with our moving cost calculator, or see where else to move from Durham.
City profiles: Durham, NC Β· St. Louis, MO.