Moving from Buffalo, NY to St. Louis, MO
The drive from Buffalo, NY to St. Louis, MO runs 747 mi β about 14h 9m on interstate, longer with stops. Long-range relocations typically bring real shifts in cost of living, housing prices, climate, and job market. Below, each of those layers is pulled from its source (BEA, Census, Zillow, BLS, NOAA) for a direct comparison.
747 mi Β· 14h 9m by car Β· MO β IL β IN β OH β PA β NY
Distance & route
| Route through | MO β IL β IN β OH β PA β NY |
|---|---|
| Primary highways | I 70, I 90, I 71 |
| Major cities en route | Dayton, Columbus, Akron, Cleveland |
Route via OSRM driving profile. Actual time varies with traffic and season.
Cost of living
| Buffalo | St. Louis | U.S. avg | |
|---|---|---|---|
| All items (RPP) | 95.844 | 95.088 | 100.0 |
| Rents | 129.489 | 69.921 | 100.0 |
| Goods | 99.693 | 99.996 | 100.0 |
| Services | 80.989 | 79.024 | 100.0 |
Overall cost of living in St. Louis and Buffalo is within Β±5% on the BEA Regional Price Parity (2024) β plan your budget on category-level differences instead.
Source: BEA Regional Price Parities (MSA-level Β· MSA-level); 2024.
Housing prices
YoY change: Buffalo +3.8%, St. Louis β. Snapshot: 2026-03. Data provided by Zillow.
Climate
| 1991β2020 normals | Buffalo | St. Louis |
|---|---|---|
| Annual avg temperature | 49Β°F | 58Β°F |
| January avg low | 19Β°F | 25Β°F |
| July avg high | 80Β°F | 90Β°F |
| Annual snowfall | 95.4" | β |
| Annual precipitation | 40.7" | 43.9" |
Climate warms by 9.2Β°F on the annual average β 48.8Β°F β 58.0Β°F.
Source: NOAA U.S. Climate Normals 1991β2020 (stations: BUFFALO, NY US, ST LOUIS SCI CTR, MO US).
Demographics
| ACS 5-year 2023 | Buffalo | St. Louis |
|---|---|---|
| Population | 276,397 | 293,109 |
| Median household income | $48,050 | $55,279 |
| Median age | 34.3 | 36.6 |
| Bachelor's degree or higher | 16.9% | 22% |
| Avg household size | 2.31 | 2.03 |
Income steps up 0.8%: $48,050 in Buffalo vs $55,279 in St. Louis.
Source: U.S. Census Bureau, ACS 5-year 2023.
Jobs & wages
Top occupations in St. Louis MSA
| Occupation | Employment | Median wage |
|---|---|---|
| Office and Administrative Support Occupations | 162,150 | $43,310 |
| Food Preparation and Serving Related Occupations | 119,600 | $29,980 |
| Transportation and Material Moving Occupations | 115,380 | $39,330 |
| Sales and Related Occupations | 108,510 | $35,500 |
| Management Occupations | 94,750 | $100,940 |
Source: BLS Occupational Employment and Wage Statistics.
Moving between New York and Missouri
State income-tax top marginal rates are from the Tax Foundation, updated annually. Check Missouri's DMV for the current deadline to transfer driver license and vehicle registration after establishing residency. Consult a tax professional for your specific filing situation β state tax treatment depends on residency, sourcing, and reciprocity agreements.
Best time to move
Moving companies typically charge 20β30% more between Memorial Day and Labor Day (peak season). October through April offers the lowest rates and better mover availability.
To avoid mid-semester school transfers, most U.S. families schedule moves between mid-June and mid-August. Public school calendars typically run late August or early September through late May or early June.
Winter driving along this route
- The Pennsylvania Turnpike between Pittsburgh and Harrisburg can see chain requirements in heavy winter storms.
- Lake-effect off Lake Ontario can shut down I-81 and I-90 for hours in winter β check 511NY.
State DOT 511 phone or web services provide real-time road conditions year-round.
Packing & arrival checklist
- Tornadoes are common April through June β identify a safe room or interior space on day one.
- Arrange utility connection (power, internet, gas, water) two weeks ahead of move-in.
- Update mailing address with USPS change-of-address within the first week post-move.
- Register to vote in Missouri after establishing residency.
Frequently asked
How does household income compare in Buffalo vs St. Louis?
Median household income on the Census ACS 5-year (2023) is $55,279 in St. Louis vs $48,050 in Buffalo β a 15.0% higher figure. Compare this against the cost-of-living gap above when budgeting.
How does the job market in St. Louis compare to Buffalo?
BLS Occupational Employment and Wage Statistics show median wages of $47,490 in the St. Louis MSA vs $48,560 in the Buffalo MSA, on total employment of 1,325,480 and 526,990 respectively. Top occupations on the destination side appear in the Jobs & wages section above.
When is the best time to move from Buffalo to St. Louis?
Moving companies usually charge 20β30% less between October and April (off-peak). Memorial Day through Labor Day is peak pricing. For a 747 mi drive, weather on the route matters too β see the timing section above for state-specific winter warnings.
How far is St. Louis, MO from Buffalo, NY?
The driving distance is 747 mi and the route typically takes 14h 9m via I 70 and I 90. The trip crosses 6 state(s). Actual time varies with traffic and season.
Is St. Louis more expensive than Buffalo?
Based on BEA Regional Price Parities (2024), overall price level in St. Louis is 0.8% lower than Buffalo (95.088 vs 95.844, U.S. average = 100). Rent and services typically carry most of this gap.
Plan the move
Estimate costs with our moving cost calculator, or see where else to move from Buffalo.
City profiles: Buffalo, NY Β· St. Louis, MO.